Ep.Fri.329 Severe Acute Pancreatitis in Pregnancy Secondary to Hypertriglyceridemia – A Case Report and Literature Review

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چکیده

Abstract Background Hypertriglyceridemia is a common and well characterized physiological phenomenon in pregnancy. Rarely does it complicate the pregnancy causing acute pancreatitis (APIP). The majority of APIP cases arise secondary to gallstones. Hyperlipidaemia induced rarer cause with relatively worse outcomes increased incidences preterm delivery pseudocyst formation. Case Report A 38-years-old woman at 29 weeks gestation presented epigastric pain. initial investigations revealed raised inflammatory markers, elevated amylase hypertriglyceridemia. diagnosis was made, prompting transfer ITU. Foetal compromise necessitated an emergency Caesarean delivery. Post-partum, her clinical condition improved NG feeding, bezafibrates IV antibiotics. Her baby transferred nearby tertiary neonatal unit no immediate complications. Discussion Hyperlipidemia requires intensive treatment. Various medical treatments for hypertriglyceridemia, such as fibrates insulin infusions, have been described. Plasmapheresis severe may benefit reducing triglycerides level. Considering maternal foetal morbidity mortality, early multidisciplinary input required treat reduce Conclusion serious rare complication current lack consensus on treatment warrants further inquiry, minimise poor outcomes. merits routine screening gestational hypertriglyceridemia are yet be elucidated; associated APIP, coupled its rising incidence justify targeted programme. Keywords Pancreatitis, Pregnancy, Hypertriglyceridemia.

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ژورنال

عنوان ژورنال: British Journal of Surgery

سال: 2021

ISSN: ['1365-2168', '0007-1323']

DOI: https://doi.org/10.1093/bjs/znab312.056